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  • 🤖 OpenAI DevDay 2025: Seven Major Announcements

🤖 OpenAI DevDay 2025: Seven Major Announcements

PLUS: New Antibiotic Targets Harmful Gut Bacteria

Welcome back AI enthusiasts!

In today’s Daily Report:

  • 🚀OpenAI DevDay 2025: Seven Major Announcements

  • 🦠New Antibiotic Targets Harmful Gut Bacteria

  • 🛠Trending Tools

  • 🥪Brief Bites

  • 💰Funding Frontlines

  • 💼Who’s Hiring?

Read Time: 3 minutes

🗞RECENT NEWS

OPENAI

🚀OpenAI DevDay 2025: Seven Major Announcements

Image Source: X/Ben Parr (i.e., @benparr/“.@OpenAI #DevDay updates (so far):”/Screenshot

OpenAI announced tons of new AI stuff at OpenAI DevDay 2025. It can be challenging to keep track of everything. So, we did it for you!

Key Details:
  1. AgentKit: Empowers anyone to effortlessly build, deploy, and manage AI Agents optimized for everyday workflows.

  2. Apps in ChatGPT: You can now interact with third-party apps directly within ChatGPT. For example, you can book vacation rentals through Airbnb.

  3. Codex Upgrades: A faster, more reliable, and better software engineering agent that autonomously writes, debugs, and deploys code.

  4. Sora 2 in the API: Developers can now integrate a version of Sora 2 that produces physically accurate videos directly into their own software.

  5. GPT-5 Pro in the API: Developers can now integrate a version of GPT-5 that produces smarter outputs directly into their own software.

  6. gpt-realtime-mini”: A cost-efficient voice generator designed to deliver natural-sounding speech.

  7. gpt-image-1-mini”: A cost-efficient image generator capable of creating photos and interpreting screenshots.

Why It’s Important:
  • OpenAI CEO Sam Altman announced that ChatGPT has officially reached over 800 million weekly active users, corresponding to an average monthly increase of more than 50 million weekly active users since February 2025.

  • AMD and OpenAI also just unveiled a strategic partnership to deploy 6 Gigawatts (GW) of computing power, starting with 1 GW of the AMD Instinct MI450 GPUs in the second half of 2026. To align incentives, AMD issued OpenAI a warrant to acquire up to 160 million shares of common stock at $0.01 per share if certain performance milestones are met. If fully exercised, OpenAI would own 10% of AMD.

AI RESEARCH

🦠New Antibiotic Targets Harmful Gut Bacteria

Image Source: Canva’s AI Image Generators/Magic Media

MIT CSAIL recently developed Enterololin,” a new antibiotic specifically designed to target harmful bacteria in your gut.

Key Details:
  • Proteins do most of the work within our cells to maintain the structure, function, and regulation of our body’s organs (e.g., heart, muscles, and skin).

  • Proteins aren’t static; they constantly wiggle, bend, and fold. These movements are crucial to their function. For example, Myosin relies on bending to initiate muscle contractions.

  • MIT CSAIL leveraged a GenAI model called DiffDock to analyze a protein’s movements and accurately predict which small molecules can fit perfectly into that protein’s constantly changing binding pockets.

Why It’s Important:
  • DiffDock enabled MIT CSAIL to design antibiotics that can precisely bind to specific proteins found only in harmful gut bacteria and destroy them.

  • Traditional antibiotics act broadly, wiping out both harmful and beneficial bacteria, which can lead to weakened immunity and increased susceptibility to infections. Enterololin doesn’t disrupt the delicate balance of your gut microbiome: the beneficial bacteria that help you digest food and produce vitamins.

PROMPT ENGINEERING TIPS

⚙️Confidence Isn’t Born, It’s Built.

Confidence isn’t the absence of doubt; it’s the ability to act in spite of it. It’s overcoming the inner critic that asks: “What if I fail?” or “Am I good enough?”

Those who possess confidence aren’t fearless; they’ve simply developed the habit of courage. In other words, confidence emerges from consistently choosing courage over comfort.

So, how do you build confidence? It’s about gaining momentum. In essence, confidence compounds with each small victory. It begins with micro-actions that lead to macro-change. For instance, setting and achieving basic daily goals can boost your self-trust.

This simple prompt turns ChatGPT into your personal confidence coach:

  • Context: I want to build my self-confidence and overcome feelings of self-doubt,

  • Clarity: but I often hesitate to act for fear of failure.

  • Guidance: Can you provide me with actionable steps to steadily improve my self-confidence, especially when facing {Insert Specific Situation}?

I want to build my self-confidence and overcome feelings of self-doubt, but I often hesitate to act for fear of failure. Can you provide me with actionable steps to steadily improve my self-confidence, especially when facing {Insert Specific Situation}?

🛠TRENDING TOOLS

🎙️Chatquick turns your ideas into a podcast.

🗣️Ito AI: Type with your voice anytime, anywhere.

🍕Menu Explain translates or visualizes any menu.

🪶Life Note: Journal alongside history’s greatest minds.

🦄Scarlett Panda creates personalized bedtime stories.

🥪BRIEF BITES

Google launched Jules Tools,” an AI-powered command line companion that offers code suggestions and fixes coding bugs directly from the terminal.

a16z published Where Startup Dollars Really Go,” which reveals the top 50 AI-based tools that startups can’t live without, like Otter.ai’s meeting summarizer.

 MIT developed CRESt,” which accelerates the discovery of new materials to tackle real-world energy constraints by autonomously performing chemical experiments.

Alibaba CEO Eddie Wu announced Roadmap to Artificial Superintelligence,” which provides a glimpse into China’s roadmap for developing machines that can think, reason, learn, and act in a way that’s smarter than humans.

💰FUNDING FRONTLINES

  • AdPipe landed a $12M Series A to help enterprises authentically brand themselves.

  • Supabase closed a $100M Series E at a $5B valuation to build AI-powered apps.

  • Vercel raised a $300M Series F at a $9.3B valuation to deploy the AI-native cloud.

💼WHO’S HIRING?

  • Meta (New York, NY): Product Security Engineer Intern, Summer 2026

  • NVIDIA (Santa Clara, CA): GenAI Algorithms Engineer, Entry-Level

  • xAI (Palo Alto, CA): Software Engineer, X Money, Mid-Level

  • Figure AI (San Jose, CA): Materials Planning Manager, Senior-Level

📒FINAL NOTE

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